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clonal diversification of lymphocytes review of last lecture bone marrow thymus whenever immature pre-t cells recognize self-antigens, they are programmed to auto-destruct in the thymus whereasmature t cells proliferate when they contact antigens 98% pre-t cells die in the thymus bone marrow when immature pre-b cells recognize self-antigens then they auto-destruct in the bone marrow clones of mature b cells proliferate when contacting antigen toleranceto self substances treatments for autoimmune diseases - wipe out the mature b c

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6 mounth ago

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